Protein Details: Gap junction beta-3 protein

Protein ID

ICDB_Pro_0261

Protein Name

Gap junction beta-3 protein

Gene Name

GJB3; CX31

Organism

Homo sapiens (Human)

Length

270 amino acids

AlphaFoldDB

AF-O75712-F1-model_v4.pdb

Function

Sequence

MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCRCHHKLVEAGEVDPDPGNNKLQASAPNLTPI

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Erythrokeratodermia Variabilis Et Progressiva 1 and Deafness;Autosomal Dominant 2B

Location

DOI ID

10.1006/bbrc.1998.9070; 10.1038/3840; 10.1038/ng1285; 10.1038/nature04727; 10.1101/gr.2596504; 10.1038/3845; 10.1046/j.1523-1747.1999.00792.x; 10.1038/sj.ejhg.5200407; 10.1007/s004390051045; 10.1093/hmg/9.1.63; 10.1002/(sici)1098-1004(200005)15:5<481::aid-humu15>3.0.co;2-7; 10.1002/ajmg.a.32765

RefSeq

NP_001005752.1; NP_076872.1